Mitofusin 2 Rabbit Polyclonal Antibody — image 1 of 3

Product details

Mitofusin 2 Rabbit Polyclonal Antibody

Catalog number ER1802-23

Price for ER1802-23

Size / count 100 µL

About this product

Mitofusin 1 (Mfn1) and mitofusin 2 (Mfn2) are homologs for the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins and are mediators of mitochondrial fusion. A GTPase domain is required for Mfn protein function but the molecular mechanisms of the GTPase-dependent reaction as well as the functional division of the two Mfn proteins are unknown. They are essential for embryonic development and may play a role in the pathobiology of obesity. Although the Mfn1 and Mfn2 genes are broadly expressed, they show different levels of expression in different tissues. Two Mfn1 transcripts are elevated in heart, while Mfn2 mRNA is abundantly expressed in heart and muscle tissue but present only at low levels in many other tissues. Mfn1 localizes to mitochondria and participates in at least two different high molecular weight protein complexes in a GTP-dependent manner. Purified recombinant Mfn1 exhibited approximately eightfold higher GTPase activity than Mfn2.

Specifications

Catalog number: ER1802-23
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CMT2A antibody CMT2A2 antibody CPRP 1 antibody CPRP1 antibody EC 3.6.5.- antibody Fzo antibody HSG antibody hyperplasia suppressor gene antibody Hypertension related protein 1 antibody KIAA0214 antibody MARF antibody MFN 2 antibody Mfn2 antibody MFN2_HUMAN antibody Mitochondrial assembly regulatory factor antibody Mitofusin-2 antibody Mitofusin2 antibody Transmembrane GTPase MFN2 antibody
Abbreviation: MFN2, CPRP1, KIAA0214
Swiss Prot: O95140 Human, Q8R500 Rat
Cellular Locus: Mitochondrion.
Host: Rabbit
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within human Mitofusin 2 aa 378-602.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, FC
Positive Control: Rat heart tissue lysates, A431, LOVO, PC-3M, Jurkat.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 86 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Mitofusin 2 Rabbit Polyclonal Antibody?

The catalog number for Mitofusin 2 Rabbit Polyclonal Antibody is ER1802-23.

What sizes are available for Mitofusin 2 Rabbit Polyclonal Antibody?

Mitofusin 2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Mitofusin 2 Rabbit Polyclonal Antibody in stock?

Mitofusin 2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mitofusin 2 Rabbit Polyclonal Antibody used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.