SATB1 Rabbit Polyclonal Antibody — image 1 of 3

Product details

SATB1 Rabbit Polyclonal Antibody

Catalog number ER1802-24

Price for ER1802-24

Size / count 100 µL

About this product

The homeoproteins CCAAT displacement protein (CDP) and special AT-rich sequence binding protein 1 (SATB1) are transcriptional repressors of many cellular genes, and they participate in cell development and cell type differentiation. SATB1 is expressed primarily in thymocytes, and, like CDP, it also contains a distinct homeobox DNA-binding domain that is essential for DNA binding. SATB1 and CDP interact through these homeodomains and synergistically function as mediators of gene expression. SATB1 contains an additional domain that has a higher affinity for DNA and specifically facilitates the direct association between SATB1 and the nuclear matrix attachment regions (MARs) of DNA. MARs are specific DNA sequences that bind to the nuclear matrix and form the base of chromosomal loops that organize the chromosomes and regulate DNA transcription and replication within the nucleus. The association of SATB1 with the core unwinding element within the base-unpairing region of MARs requires both the MAR and homeobox binding domains of SATB1.

Specifications

Catalog number: ER1802-24
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: DNA binding protein SATB1 antibody DNA-binding protein SATB1 antibody SATB homeobox 1 antibody SATB1 antibody SATB1_HUMAN antibody Special AT rich sequence binding protein 1 (binds to nuclear matrix/scaffold associating DNA) antibody Special AT rich sequence binding protein 1 antibody Special AT-rich sequence-binding protein 1 antibody
Abbreviation: SATB1
Swiss Prot: Q01826 Human, Q60611 Mouse
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within N-terminal human SATB1 aa.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, FC
Positive Control: Mouse thymus tissue lysate,SH-SY-5Y, Jurkat.
Concentration: 1 mg/mL
Dilution: WB: 1:500;IF-Cell: 1:100;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size 86 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for SATB1 Rabbit Polyclonal Antibody?

The catalog number for SATB1 Rabbit Polyclonal Antibody is ER1802-24.

What sizes are available for SATB1 Rabbit Polyclonal Antibody?

SATB1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is SATB1 Rabbit Polyclonal Antibody in stock?

SATB1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is SATB1 Rabbit Polyclonal Antibody used for?

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.