USP21 Rabbit Polyclonal Antibody

About this product

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP21 (ubiquitin specific peptidase 21), also known as USP16 or USP23, is a 565 amino acid protein that belongs to the C19 peptidase family of ubiquitin carboxy-terminal hydrolases. Capable of removing ubiquitin from ubiquitinated proteins, USP21 plays a role in signal transduction and can also remove NEDD8 from NEDD8-conjugated proteins, possibly functioning to influence NEDD8-mediated protein proteolysis. Multiple isoforms of USP21 exist due to alternative splicing events.

Specifications

Catalog number

ER1802-25

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

Deubiquitinating enzyme 21 antibody deubiquitinating enzyme 23 antibody EC 3.1.2.15 antibody ESTM28 antibody MGC3394 antibody NEDD8-specific protease antibody Ubiquitin carboxyl terminal hydrolase 21 antibody ubiquitin carboxyl terminal hydrolase 23 antibody Ubiquitin carboxyl-terminal hydrolase 21 antibody ubiquitin specific peptidase 21 antibody Ubiquitin specific processing protease 21 antibody ubiquitin specific protease 16 antibody ubiquitin specific protease 21 antibody ubiquitin specific protease 23 antibody Ubiquitin thioesterase 21 antibody Ubiquitin thiolesterase 21 antibody ubiquitin thiolesterase 23 antibody ubiquitin-specific protease 23, formerly antibody Ubiquitin-specific-processing protease 21 antibody UBP21_HUMAN antibody USP16 antibodyv Usp21 antibody USP23 antibody USP23, formerly antibody W53272 antibody

Abbreviation

USP21, USP23, PP1490

Swiss Prot

Q9UK80 Human, Q9QZL6 Mouse, B2GUX4 Rat

Cellular Locus

Cytoplasm. Nucleus.

Host

Rabbit

Species Reactivity

Human, Rat, Mouse

Immunogen

Synthetic peptide within Human USP21 aa 1-50 / 565.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Mouse thymus tissue lysate, PC-3M, SH-SY-5Y, human liver cancer tissue, human kidney tissue, human fetal skeletal muscle tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500;IF-Cell: 1:500-1:2,000;IHC-P: 1:50-1:200;FC: 1:50-1:100

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

63 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No