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Product details

Fusion glycoprotein F0 Rabbit Polyclonal Antibody

Catalog number ER1802-33

Price for ER1802-33

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Size / count 100 µL

About this product

During virus entry, induces fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2. Interacts directly with heparan sulfate and may participate in virus attachment. Furthermore, the F2 subunit was identifed as the major determinant of RSV host cell specificity. Later in infection, proteins F expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis. The fusion protein is also able to trigger p53-dependent apoptosis.

Specifications

Catalog number
ER1802-33
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
F antibody Fusion glycoprotein F0 antibody Protein F antibody RSV Fusion (F) Glycoprotein antibody
Abbreviation
F
Swiss Prot
W8CLH7 Avian avulavirus 1
Cellular Locus
Host cell membrane. Virion membrane.
Host
Rabbit
Species Reactivity
Avian avulavirus 1
Immunogen
Synthetic peptide within newcastle disease virus Fusion glycoprotein F0 aa 86-135 / 553.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, ELISA
Positive Control
Fusion glycoprotein F0 transfected HEK293 cell.
Concentration
1 mg/mL
Dilution
WB: 1:500-1,000;ELISA: 1:5,000-1:10,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
59 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Fusion glycoprotein F0 Rabbit Polyclonal Antibody?

The catalog number for Fusion glycoprotein F0 Rabbit Polyclonal Antibody is ER1802-33.

What sizes are available for Fusion glycoprotein F0 Rabbit Polyclonal Antibody?

Fusion glycoprotein F0 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Fusion glycoprotein F0 Rabbit Polyclonal Antibody in stock?

Fusion glycoprotein F0 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Fusion glycoprotein F0 Rabbit Polyclonal Antibody used for?

During virus entry, induces fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2. Interacts directly with h

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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