APC Rabbit Polyclonal Antibody — image 1 of 3

Product details

APC Rabbit Polyclonal Antibody

Catalog number ER1802-39

Price for ER1802-39

Size / count 100 µL

About this product

The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner's syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. The cloning of the APC gene revealed a ubiquitously expressed protein, 2,843 amino acids in length, which is frequently mutated in patients suffering from FAP and GS. APC has been found to be associated with structural components of intracellular junctions. β-catenin and γ-catenin (also called plakoglobin), are involved in the regulation of cellular adhesion. APC and E-cadherin compete for binding to specific internal regions of both β- and γ-catenin. Interactions between cytoskeleton and the APC, E-cadherin, β/γ catenin complex are mediated by α-catenin.

Specifications

Catalog number: ER1802-39
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Adenomatous Polyposis Coli antibody Adenomatous polyposis coli protein antibody Apc antibody APC_HUMAN antibody CC1 antibody Deleted in polyposis 2.5 antibody DP2 antibody DP2.5 antibody DP3 antibody FAP antibody FPC antibody GS antibody Protein APC antibody
Abbreviation: APC, DP2.5
Swiss Prot: P25054 Human, Q61315 Mouse, P70478 Rat
Cellular Locus: Cell junction. Cytoplasm. Cytoskeleton. Membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within C-terminal human Ifna1.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC, IF-Tissue, IHC-Fr
Positive Control: HUVEC, SH-SY-5Y, SiHa, human kidney tissue, mouse kidney tissue, rat kidney tissue.
Concentration: 1 mg/mL
Dilution: IF-Cell: 1:50-1:200 ;IHC-P: 1:1,000 ;FC: 1:50-1:100 ;WB: 1:500 ;IF-Tissue: 1:200 ;IHC-Fr: 1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 312 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for APC Rabbit Polyclonal Antibody?

The catalog number for APC Rabbit Polyclonal Antibody is ER1802-39.

What sizes are available for APC Rabbit Polyclonal Antibody?

APC Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is APC Rabbit Polyclonal Antibody in stock?

APC Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is APC Rabbit Polyclonal Antibody used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.