Vitamin D Receptor Rabbit Polyclonal Antibody — image 1 of 2

Product details

Vitamin D Receptor Rabbit Polyclonal Antibody

Catalog number ER1802-40

Price for ER1802-40

Size / count 100 µL

About this product

The active metabolite of vitamin D modulates the expression of a wide variety of genes in a developmentally specific manner. This secosteroid hormone can up- or downregulate the expression of genes involved in a diverse array of responses such as proliferation, differentiation and calcium homeostasis. 1,25- (OH)2-vitamin D3 exerts its effects through interaction with the vitamin D receptor (VDR), a member of the superfamily of hormone-activated nuclear receptors. In its ligand-bound state, the VDR forms heterodimers with the 9-cis retinoic acid receptor, RXR, and affects gene expression by binding specific DNA sequences known as hormone response elements, or HREs. In addition to regulating the above-mentioned cellular responses, 1,25- (OH)2-vitamin D3 exhibits antiproliferative properties in osteosarcoma, melanoma, colon carcinoma and breast carcinoma cells.

Specifications

Catalog number: ER1802-40
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 1 25 dihydroxyvitamin D3 receptor antibody 1 antibody 1,25 dihydroxyvitamin D3 receptor antibody 1,25-@dihydroxyvitamin D3 receptor antibody 25-dihydroxyvitamin D3 receptor antibody Member 1 antibody NR1I1 antibody Nuclear receptor subfamily 1 group I member 1 antibody PPP1R163 antibody Protein phosphatase 1, regulatory subunit 163 antibody VDR antibody VDR_HUMAN antibody Vitamin D (1,25- dihydroxyvitamin D3) receptor antibody Vitamin D hormone receptor antibody Vitamin D nuclear receptor variant 1 antibody Vitamin D receptor antibody Vitamin D3 receptor antibody
Abbreviation: VDR, NR1I1
Swiss Prot: P11473 Human
Cellular Locus: Nucleus. Cytoplasm.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human Vitamin D Receptor aa 371-420 / 427.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, FC
Positive Control: PC-3M, Human small intestine tissue lysate, LOVO.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 48 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Vitamin D Receptor Rabbit Polyclonal Antibody?

The catalog number for Vitamin D Receptor Rabbit Polyclonal Antibody is ER1802-40.

What sizes are available for Vitamin D Receptor Rabbit Polyclonal Antibody?

Vitamin D Receptor Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Vitamin D Receptor Rabbit Polyclonal Antibody in stock?

Vitamin D Receptor Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Vitamin D Receptor Rabbit Polyclonal Antibody used for?

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.