Raptor Rabbit Polyclonal Antibody

About this product

Regulatory associated protein of FRAP, also designated Raptor, is a binding partner for mammalian target of rapamycin kinase (FRAP), and is essential for FRAP signalling in vivo. Raptor binding to FRAP is critical for FRAP-catalysed substrate phosphorylation of 4E-BP1. The raptor-FRAP complex is nutrient-sensitive and is important for a mechanism by which cells coordinate cell growth and size with changing environmental conditions. Raptor serves as a negative regulator of FRAP kinase activity under nutrient-deprived conditions and is an important component in the FRAP pathway. Raptor is highly expressed in skeletal muscle and to a lesser extent in brain, kidney, lung and placenta.

Specifications

Catalog number

ER1802-57

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

KIAA1303 antibody KOG1 antibody Mip1 antibody P150 target of rapamycin (TOR) scaffold protein antibody p150 target of rapamycin (TOR) scaffold protein containing WD repeats antibody P150 target of rapamycin (TOR)-scaffold protein antibody Raptor antibody Regulatory associated protein of mTOR antibody Regulatory associated protein of MTOR complex 1 antibody Regulatory-associated protein of mTOR antibody RPTOR antibody RPTOR_HUMAN antibody

Abbreviation

Raptor, RPTOR, KIAA1303, RAPTOR

Swiss Prot

Q8N122 Human, Q8K4Q0 Mouse,

Cellular Locus

Cytoplasm, Lysosome, Cytoplasmic granule.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human Raptor aa 90-170.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

MCF-7 cell lysates, 293T, LOVO, rat brain tissue, human breast tissue, mouse colon tissue, A549.

Concentration

1 mg/mL

Dilution

WB: 1:500;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 149 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No