Tle6 Rabbit Polyclonal Antibody — image 1 of 3

Product details

Tle6 Rabbit Polyclonal Antibody

Catalog number ER1802-58

Price for ER1802-58

Size / count 100 µL

About this product

The Notch signaling pathway controls various cellular interactions that are important for the specification of a variety of fates in both vertebrates and invertebrates. Key players in the Notch pathway are the TLE genes (for transducin-like enhancer of split, also designated ESG for enhancer of split groucho), which are human homologs of the Drosophila groucho gene. TLE6 (transducin-like enhancer of split 6), also known as GRG6, is a 449 amino acid cytoplasmic protein belonging to the WD repeat groucho/TLE family. As a member of the subcortical maternal complex (SCMC), TLE6 is essential for zygotes to progress beyond the first embryonic cell divisions. TLE6 contains seven WD repeats, a motif known to mediate protein-protein interactions. The WD40 repeat family of proteins is suggested to be involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation.

Specifications

Catalog number: ER1802-58
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Transducin-like enhancer protein 6 TLE6
Abbreviation: TLE6
Swiss Prot: Q9H808 Human, Q9WVB3 Mouse
Cellular Locus: Nucleus. Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within mouse Tle6 aa 157-206 / 581.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Mouse ovary tissue lysate, HepG2, A431, A549, SK-Br-3, mouse small intestine tissue, Daudi.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 63 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Tle6 Rabbit Polyclonal Antibody?

The catalog number for Tle6 Rabbit Polyclonal Antibody is ER1802-58.

What sizes are available for Tle6 Rabbit Polyclonal Antibody?

Tle6 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Tle6 Rabbit Polyclonal Antibody in stock?

Tle6 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Tle6 Rabbit Polyclonal Antibody used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.