NGF Rabbit Polyclonal Antibody

About this product

Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. It is perhaps the prototypical growth factor, in that it was one of the first to be described. Since it was first isolated by Nobel Laureates Rita Levi-Montalcini and Stanley Cohen in 1956, numerous biological processes involving NGF have been identified, two of them being the survival of pancreatic beta cells and the regulation of the immune system. As its name suggests, NGF is involved primarily in the growth, as well as the maintenance, proliferation, and survival of nerve cells (neurons). In fact, NGF is critical for the survival and maintenance of sympathetic and sensory neurons, as they undergo apoptosis in its absence. However, several recent studies suggest that NGF is also involved in pathways besides those regulating the life cycle of neurons.

Specifications

Catalog number

ER1802-59

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

Beta nerve growth factor antibody Beta NGF antibody Beta-nerve growth factor antibody Beta-NGF antibody HSAN5 antibody MGC161426 antibody MGC161428 antibody Nerve growth factor (beta polypeptide) antibody Nerve growth factor antibody Nerve growth factor beta antibody Nerve growth factor beta polypeptide antibody Nerve growth factor beta subunit antibody NGF antibody NGF_HUMAN antibody NGFB antibody NID67 antibody

Abbreviation

Beta-NGF, NGF, NGFB

Swiss Prot

P01138 Human, P01139 Mouse, P25427 Rat

Cellular Locus

Secreted, Endosome lumen.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human NGF aa 119-158 / 241.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

N2A, SHG-44, SH-SY-5Y, rat brain tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 27 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No