T-bet Rabbit Polyclonal Antibody — image 1 of 2

Product details

T-bet Rabbit Polyclonal Antibody

Catalog number ER1802-65

Price for ER1802-65

Size / count 100 µL

About this product

T helper (Th) lymphocytes differentiate into two unique subsets, Th1 and Th2, which differ both in function and in the cytokines they secrete. Th1 and Th2 cytokines promote the growth and differentiation of their subset, and inhibit the growth and differentiation of the opposing subset. T-bet (T box expressed in T cells) is a Th1-specific T box transcription factor that controls the expres-sion of the Th1 cytokine, IFN-γ. T-bet also converts effector Th2 cells into the opposing Th1 subset. T-bet is selectively expressed in Th1 cells. The level of T-bet expression is increased by signals mediated by the T cell receptor (TCR). IL-12 also induces an increase in the level of T-bet. T-bet was originally isolated from nuclear extracts of resting and PMA/ionomycin-activated AE7 cells. T-bet is expressed in low levels in AE7 cells, and in increased levels in stimulated AE7.

Specifications

Catalog number: ER1802-65
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: T bet antibody T box 21 antibody T box expressed in T cells antibody T box protein 21 antibody T box transcription factor TBX21 antibody T cell specific T box transcription factor antibody T cell specific T box transcription factor T bet antibody T PET antibody T-box protein 21 antibody T-box transcription factor TBX21 antibody T-cell-specific T-box transcription factor T-bet antibody TBET antibody TBLYM antibody TBX 21 antibody Tbx21 antibody TBX21_HUMAN antibody TPET antibody Transcription factor TBLYM antibody
Abbreviation: T-box protein 21, Tbx21, Tbet, Tblym
Swiss Prot: Q9UL17 Human, Q9JKD8 Mouse
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within Human T-bet aa 486-535 / 535.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, FC, IHC-P
Positive Control: Mouse marrow tissue lysate, Jurkat, human lymph nodes tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500 ;FC: 1ug/mL ;IHC-P: 1:500
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 58 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for T-bet Rabbit Polyclonal Antibody?

The catalog number for T-bet Rabbit Polyclonal Antibody is ER1802-65.

What sizes are available for T-bet Rabbit Polyclonal Antibody?

T-bet Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is T-bet Rabbit Polyclonal Antibody in stock?

T-bet Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is T-bet Rabbit Polyclonal Antibody used for?

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.