PARP1 Rabbit Polyclonal Antibody — image 1 of 3

Product details

PARP1 Rabbit Polyclonal Antibody

Catalog number ER1802-67

Price for ER1802-67

Size / count 100 µL

About this product

Involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly (ADP-ribosyl)ation of APLF and CHFR. Positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. With EEF1A1 and TXK, forms a complex that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. Required for PARP9 and DTX3L recruitment to DNA damage sites. PARP1-dependent PARP9-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites.

Specifications

Catalog number: ER1802-67
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: ADP ribosyltransferase (NAD+; poly (ADP ribose) polymerase) antibody ADP ribosyltransferase antibody ADP ribosyltransferase diphtheria toxin like 1 antibody ADP ribosyltransferase NAD (+) antibody ADPRT 1 antibody ADPRT antibody ADPRT1 antibody ARTD1 antibody msPARP antibody NAD (+) ADP ribosyltransferase 1 antibody NAD (+) ADP-ribosyltransferase 1 antibody pADPRT 1 antibody pADPRT1 antibody PARP 1 antibody PARP antibody PARP-1 antibody PARP1 antibody PARP1_HUMAN antibody Poly (ADP ribose) polymerase 1 antibody poly (ADP ribose) polymerase family, member 1 antibody Poly [ADP-ribose] polymerase 1 antibody Poly (ADP ribose) polymerase antibody poly (ADP ribose) synthetase antibody poly (ADP ribosyl)transferase antibody Poly[ADP ribose] synthetase 1 antibody Poly[ADP-ribose] synthase 1 antibody PPOL antibody
Abbreviation: PARP-1, ARTD1, ADPRT 1, PARP1, ADPRT, PPOL
Swiss Prot: P09874 Human
Cellular Locus: Nucleus, nucleolus, Cytoplasm, cytosol.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within PARP1 aa 190-270.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, FC
Positive Control: Daudi, 293, A431, SH-SY5Y, K562.
Concentration: 1 mg/mL
Dilution: WB: 1:500 ;IF-Cell: 1:50-1:100 ;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 113 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PARP1 Rabbit Polyclonal Antibody?

The catalog number for PARP1 Rabbit Polyclonal Antibody is ER1802-67.

What sizes are available for PARP1 Rabbit Polyclonal Antibody?

PARP1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PARP1 Rabbit Polyclonal Antibody in stock?

PARP1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PARP1 Rabbit Polyclonal Antibody used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.