EpCAM Rabbit Polyclonal Antibody

About this product

The epithelial cell adhesion molecule Ep-CAM, which is also designated tumor-associated calcium signal transducer 1 and MK-1, is a monomeric membrane glycoprotein that is expressed in most normal human epithelium and carcinomas. The human Ep-CAM gene encodes a 314 amino acid protein that is expressed as two forms, a major form and a minor form, which are reduced upon treatment with the amino-glycosylation inhibitor tunicamycin. Ep-CAM is overexpressed in a variety of carcinomas and is, therefore, a potential target for the visualization and therapy of human solid tumors. Ep-CAM contains an extracellular domain containing two epidermal growth factor-like repeats, followed by a cysteine poor region, which is necessary for the adhesion properties of the molecule.

Specifications

Catalog number

ER1802-80

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

17 1A antibody 323/A3 antibody Adenocarcinoma associated antigen antibody Adenocarcinoma-associated antigen antibody Antigen identified by monoclonal antibody AUA1 antibody AUA1 antibody CD326 antibody CD326 antigen antibody Cell surface glycoprotein Trop 1 antibody Cell surface glycoprotein Trop 2 antibody Cell surface glycoprotein Trop-1 antibody CO 17A antibody CO17 1A antibody CO17A antibody DIAR5 antibody EGP 2 antibody EGP antibody EGP2 antibody EGP314 antibody EGP40 antibody Ep CAM antibody Ep-CAM antibody EPCAM antibody EPCAM_HUMAN antibody EpCAM1 antibody Epithelial cell adhesion molecule antibody Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) antibody Epithelial cell surface antigen antibody Epithelial cellular adhesion molecule antibody Epithelial glycoprotein 1 antibody Epithelial glycoprotein 314 antibody Epithelial glycoprotein antibody ESA antibody GA733 1 antibody GA733 2 antibody GA733-2 antibody gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein antibody gp4 antibody hEGP 2 antibody hEGP314 antibody HNPCC8 antibody Human epithelial glycoprotein 2 antibody KS 1/4 antigen antibody KS1/4 antibody KSA antibody Ly74 antibody Lymphocyte antigen 74 antibody M1S 1 antibody M1S2 antibody M4S1 antibody Major gastrointestinal tumor associated protein GA733 2 antibody Major gastrointestinal tumor-associated protein GA733-2 antibody mEGP314 antibody Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody Membrane component, chromosome 4, surface marker 1 antibody Membrane component, chromosome 4, surface marker antibody MIC18 antibody MK 1 antibody Protein 289A antibody TACD1 antibody TACSTD1 antibody TROP1 antibody Tumor associated calcium signal transducer 1 antibody Tumor associated calcium signal transducer 2 precursor antibody Tumor-associated calcium signal transducer 1 antibody

Abbreviation

Ep-CAM, EGP, EGP314, hEGP314, EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1

Swiss Prot

P16422 Human, Q99JW5 Mouse, O55159 Rat

Cellular Locus

Cell junction, Plasma membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human EpCAM aa 90-180.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

Mouse colon tissue lysate, LOVO, MCF-7, rat epididymis tissue, human colon cancer tissue, mouse small intestine tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IHC-P: 1:50-1:200

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 35 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No