ASK1 Rabbit Polyclonal Antibody — image 1 of 3

Product details

ASK1 Rabbit Polyclonal Antibody

Catalog number ER1802-84

Price for ER1802-84

Size / count 100 µL

About this product

Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4, ASK 1 (MEK kinase-5) and MAP3K6 (MEK kinase-6). MEK kinase-1 has been shown to phosphorylate MEK-1 via a Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK pathway. ASK1 activates both MEK-4 and MEK-3/MEK-6 pathways.

Specifications

Catalog number: ER1802-84
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Apoptosis signal regulating kinase 1 antibody Apoptosis signal-regulating kinase 1 antibody ASK 1 antibody ASK-1 antibody ASK1 antibody M3K5 antibody M3K5_HUMAN antibody MAP/ERK kinase kinase 5 antibody MAP3K5 antibody MAPK/ERK kinase kinase 5 antibody MAPKKK5 antibody MEK kinase 5 antibody MEKK 5 antibody MEKK5 antibody Mitogen activated protein kinase kinase kinase 5 antibody Mitogen-activated protein kinase kinase kinase 5 antibody
Abbreviation: ASK-1, MEK kinase 5, MEKK 5, MAP3K5, ASK1, MAPKKK5, MEKK5
Swiss Prot: Q99683 Human, O35099 Mouse
Cellular Locus: Cytoplasm, Endoplasmic reticulum.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide of C-terminal human ASK1.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: Human skeletal muscle tissue lysate, human colon cancer tissue, mouse testis tissue, PANC-1.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 155 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for ASK1 Rabbit Polyclonal Antibody?

The catalog number for ASK1 Rabbit Polyclonal Antibody is ER1802-84.

What sizes are available for ASK1 Rabbit Polyclonal Antibody?

ASK1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is ASK1 Rabbit Polyclonal Antibody in stock?

ASK1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is ASK1 Rabbit Polyclonal Antibody used for?

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.