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Product details

Glutathione Reductase Rabbit Polyclonal Antibody

Catalog number ER1802-96

Price for ER1802-96

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Size / count 100 µL

About this product

Glutathione plays a key role in maintaining proper function and preventing oxidative stress in human cells. It can act as a scavenger for hydroxyl radicals, singlet oxygen, and various electrophiles. Reduced glutathione reduces the oxidized form of the enzyme glutathione peroxidase, which in turn reduces hydrogen peroxide (H2O2), a dangerously reactive species within the cell. In addition, it plays a key role in the metabolism and clearance of xenobiotics, acts as a cofactor in certain detoxifying enzymes, participates in transport, and regenerates antioxidants such and Vitamins E and C to their reactive forms. The ratio of GSSG/GSH present in the cell is a key factor in properly maintaining the oxidative balance of the cell, that is, it is critical that the cell maintains high levels of the reduced glutathione and a low level of the oxidized Glutathione disulfide. This narrow balance is maintained by glutathione reductase, which catalyzes the reduction of GSSG to GSH.

Specifications

Catalog number
ER1802-96
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
GLR1 antibody GLUR antibody Glutathione reductase antibody Glutathione reductase mitochondrial antibody Glutathione reductase, mitochondrial antibody GR antibody Gr1 antibody GRase antibody GRD 1 antibody GRD1 antibody GSHR_HUMAN antibody GSR antibody MGC78522 antibody
Abbreviation
GR, GRase, GSR, GLUR, GRD1
Swiss Prot
P00390 Human, P70619 Rat
Cellular Locus
Cytoplasm. Mitochondrion.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within Human GLUR aa 273-446 / 522.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
A549, rat liver tissue, rat epididymis tissue, human liver tissue, human thyroid gland tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 56 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Glutathione Reductase Rabbit Polyclonal Antibody?

The catalog number for Glutathione Reductase Rabbit Polyclonal Antibody is ER1802-96.

What sizes are available for Glutathione Reductase Rabbit Polyclonal Antibody?

Glutathione Reductase Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Glutathione Reductase Rabbit Polyclonal Antibody in stock?

Glutathione Reductase Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Glutathione Reductase Rabbit Polyclonal Antibody used for?

Glutathione plays a key role in maintaining proper function and preventing oxidative stress in human cells. It can act as a scavenger for hydroxyl radicals, singlet oxygen, and various electrophiles. Reduced glutathione reduces the oxidized form of the enzyme glutathione peroxidase, which in turn re

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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