Orai1 Rabbit Polyclonal Antibody — image 1 of 3

Product details

Orai1 Rabbit Polyclonal Antibody

Catalog number ER1803-11

Price for ER1803-11

Size / count 100 µL

About this product

Orai1 (ORAI calcium release-activated calcium modulator 1), also known as ORAT1, CRACM1 (calcium release-activated calcium modulator 1) or TMEM142A (transmembrane protein 142A), is a 301 amino acid multi-pass membrane protein that belongs to the Orai family of proteins. Localizing to the plasma membrane, Orai1 plays an important role in store-operated calcium (SOC) entry, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca2+ mobilizing agents. Specifically, Orai1 functions as a pore subunit of the store-operated calcium release-activated calcium channel (CRAC) and is essential for proper function of the CRAC channel. CRAC channels are responsible for mediating calcium influx in T-cells and play an important role in the immune response. Mutations in the gene encoding Orai1 can result in severe combined immunodeficiency (SCID).

Specifications

Catalog number: ER1803-11
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Calcium release activated calcium channel protein 1 antibody Calcium release activated calcium modulator 1 antibody Calcium release-activated calcium channel protein 1 antibody CRACM 1 antibody CRACM1 antibody CRCM1 antibody CRCM1_HUMAN antibody FLJ14466 antibody Orai 1 antibody ORAI calcium release activated calcium modulator 1 antibody orai1 antibody ORAT1 antibody Protein orai 1 antibody Protein orai-1 antibody TMEM 142A antibody TMEM142A antibody Transmembrane protein 142A antibody
Abbreviation: ORAI1, CRACM1, TMEM142A
Swiss Prot: Q96D31 Human, Q8BWG9 Mouse
Cellular Locus: Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within mouse Orai1 aa 181-230 / 304.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: PC-3M, LOVO, MCF-7, human skin tissue, human esophagus tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 33 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Orai1 Rabbit Polyclonal Antibody?

The catalog number for Orai1 Rabbit Polyclonal Antibody is ER1803-11.

What sizes are available for Orai1 Rabbit Polyclonal Antibody?

Orai1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Orai1 Rabbit Polyclonal Antibody in stock?

Orai1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Orai1 Rabbit Polyclonal Antibody used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.