Vitamin D3 Receptor Rabbit Polyclonal Antibody — image 1 of 3

Product details

Vitamin D3 Receptor Rabbit Polyclonal Antibody

Catalog number ER1803-18

Price for ER1803-18

Size / count 100 µL

About this product

The active metabolite of vitamin D modulates the expression of a wide variety of genes in a developmentally specific manner. This secosteroid hormone can up- or downregulate the expression of genes involved in a diverse array of responses such as proliferation, differentiation and calcium homeostasis. 1,25- (OH)2-vitamin D3 exerts its effects through interaction with the vitamin D receptor (VDR), a member of the superfamily of hormone-activated nuclear receptors. In its ligand-bound state, the VDR forms heterodimers with the 9-cis retinoic acid receptor, RXR, and affects gene expression by binding specific DNA sequences known as hormone response elements, or HREs. In addition to regulating the above-mentioned cellular responses, 1,25- (OH)2-vitamin D3 exhibits antiproliferative properties in osteosarcoma, melanoma, colon carcinoma and breast carcinoma cells.

Specifications

Catalog number: ER1803-18
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 1 25 dihydroxyvitamin D3 receptor antibody 1 antibody 1,25 dihydroxyvitamin D3 receptor antibody 1,25-@dihydroxyvitamin D3 receptor antibody 25-dihydroxyvitamin D3 receptor antibody Member 1 antibody NR1I1 antibody Nuclear receptor subfamily 1 group I member 1 antibody PPP1R163 antibody Protein phosphatase 1, regulatory subunit 163 antibody VDR antibody VDR_HUMAN antibody Vitamin D (1,25- dihydroxyvitamin D3) receptor antibody Vitamin D hormone receptor antibody Vitamin D nuclear receptor variant 1 antibody Vitamin D receptor antibody Vitamin D3 receptor antibody
Abbreviation: VDR, NR1I1
Swiss Prot: P11473 Human, P13053 Rat
Cellular Locus: Nucleus, Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within Human Vitamin D Receptor aa 117-297 / 427.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, FC
Positive Control: U937, SK-Br-3, LOVO, MCF-7, PC-3M, rat skin tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000;IF-Cell: 1:50-1:200;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 48 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Vitamin D3 Receptor Rabbit Polyclonal Antibody?

The catalog number for Vitamin D3 Receptor Rabbit Polyclonal Antibody is ER1803-18.

What sizes are available for Vitamin D3 Receptor Rabbit Polyclonal Antibody?

Vitamin D3 Receptor Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Vitamin D3 Receptor Rabbit Polyclonal Antibody in stock?

Vitamin D3 Receptor Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Vitamin D3 Receptor Rabbit Polyclonal Antibody used for?

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.