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Product details

RYR1 Rabbit Polyclonal Antibody

Catalog number ER1803-19

Price for ER1803-19

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Size / count 100 µL

About this product

Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+ leaking into the cytoplasm. Can also mediate the release of Ca2+ from intracellular stores in neurons, and may thereby promote prolonged Ca2+ signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis.

Specifications

Catalog number
ER1803-19
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Arrhythmogenic right ventricular dysplasia 2 antibody ARVC2 antibody ARVD2 antibody Brain ryanodine receptor calcium release channel antibody Brain type ryanodine receptor antibody Cardiac muscle ryanodine receptor calcium release channel antibody Cardiac muscle type ryanodine receptor antibody CCO antibody Central core disease of muscle antibody HBRR antibody hRYR 2 antibody hRYR2 antibody MHS antibody MHS1 antibody Ryanodine receptor 1 (skeletal) antibody Ryanodine receptor 1 antibody Ryanodine receptor 2 (cardiac) antibody Ryanodine receptor 2 antibody Ryanodine receptor 3 antibody Ryanodine receptor type1 antibody RYDR antibody RYR 1 antibody RYR 2 antibody RYR 3 antibody RYR antibody RYR-1 antibody RyR1 antibody RYR1_HUMAN antibody RYR2 antibody RYR3 antibody Sarcoplasmic reticulum calcium release channel antibody Skeletal muscle calcium release channel antibody Skeletal muscle ryanodine receptor antibody Skeletal muscle type ryanodine receptor antibody Skeletal muscle-type ryanodine receptor antibody SKRR antibody Type 1 like ryanodine receptor antibody Type 1 ryanodine receptor antibody VTSIP antibody
Abbreviation
RYR-1, RyR1, RYR1, RYDR
Swiss Prot
P21817 Human, E9PZQ0 Mouse, F1LMY4 Rat
Cellular Locus
Sarcoplasmic reticulum membrane.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within Human RYR1 aa 1,354-1,403 / 5,038.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
Dot Blot, IHC-P, FC
Positive Control
Human fetal skeletal muscle tissue, mouse cerebellum tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue, SiHa.
Concentration
1 mg/mL
Dilution
Dot Blot: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 565 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for RYR1 Rabbit Polyclonal Antibody?

The catalog number for RYR1 Rabbit Polyclonal Antibody is ER1803-19.

What sizes are available for RYR1 Rabbit Polyclonal Antibody?

RYR1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is RYR1 Rabbit Polyclonal Antibody in stock?

RYR1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is RYR1 Rabbit Polyclonal Antibody used for?

Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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