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Product details

RYR2 Rabbit Polyclonal Antibody

Catalog number ER1803-22

Price for ER1803-22

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Size / count 100 µL

About this product

Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.

Specifications

Catalog number
ER1803-22
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Arrhythmogenic right ventricular dysplasia 2 antibody ARVC2 antibody ARVD2 antibody Brain ryanodine receptor calcium release channel antibody Brain type ryanodine receptor antibody Cardiac muscle ryanodine receptor calcium release channel antibody Cardiac muscle type ryanodine receptor antibody CCO antibody Central core disease of muscle antibody HBRR antibody hRYR 2 antibody hRYR2 antibody MHS antibody MHS1 antibody Ryanodine receptor 1 (skeletal) antibody Ryanodine receptor 1 antibody Ryanodine receptor 2 (cardiac) antibody Ryanodine receptor 2 antibody Ryanodine receptor 3 antibody Ryanodine receptor type1 antibody RYDR antibody RYR 1 antibody RYR 2 antibody RYR 3 antibody RYR antibody RYR-1 antibody RyR1 antibody RYR1_HUMAN antibody RYR2 antibody RYR3 antibody Sarcoplasmic reticulum calcium release channel antibody Skeletal muscle calcium release channel antibody Skeletal muscle ryanodine receptor antibody Skeletal muscle type ryanodine receptor antibody Skeletal muscle-type ryanodine receptor antibody SKRR antibody Type 1 like ryanodine receptor antibody Type 1 ryanodine receptor antibody VTSIP antibody
Abbreviation
RYR-2, RyR2, hRYR-2, RYR2
Swiss Prot
Q92736 Human, E9Q401 Mouse, B0LPN4 Rat
Cellular Locus
Membrane. Sarcoplasmic reticulum.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human RYR2 aa 1,471-1,520 / 4,967.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
293T, LOVO, SH-SY-5Y, Siha, human fetal skeletal muscle tissue, mouse brain tissue, mouse cerebellum tissue, rat skeletal muscle tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
565 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for RYR2 Rabbit Polyclonal Antibody?

The catalog number for RYR2 Rabbit Polyclonal Antibody is ER1803-22.

What sizes are available for RYR2 Rabbit Polyclonal Antibody?

RYR2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is RYR2 Rabbit Polyclonal Antibody in stock?

RYR2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is RYR2 Rabbit Polyclonal Antibody used for?

Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

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