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Product details

Eg5 Rabbit Polyclonal Antibody

Catalog number ER1803-25

Price for ER1803-25

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Size / count 100 µL

About this product

Eukaryotes contain a superfamily of microtubule-based motor proteins comprising kinesin and a number of related proteins that are thought to participate in various forms of intracellular motility, including cell division and organelle transport. KIF11 (also known as kinesin family member 11, Eg5 or TRIP5) is a slow, plus-end-directed microtubule-based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. When the expression of KIF11 is blocked, centrosome migration halts and cells are arrested in mitosis with monoastral microtubule arrays. KIF11 is phosphorylated on serine during S phase and on both serine and Thr 927 during mitosis, which regulates the association of Eg5 with the spindle apparatus (probably during early prophase). KIF11 is also known to be a member of the thyroid receptor interacting protein (Trip) family, and interacts with the thyroid hormone receptor only in the presence of thyroid hormone.

Specifications

Catalog number
ER1803-25
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
EG5 antibody HKSP antibody KIF11 antibody KIF11_HUMAN antibody Kinesin family member 11 antibody Kinesin like protein 1 antibody Kinesin-like protein 1 antibody Kinesin-like protein KIF11 antibody Kinesin-like spindle protein HKSP antibody Kinesin-related motor protein Eg5 antibody KNSL1 antibody MCLMR antibody Thyroid receptor-interacting protein 5 antibody TR-interacting protein 5 antibody TRIP-5 antibody TRIP5 antibody
Abbreviation
TR-interacting protein 5, TRIP-5, KIF11, EG5, KNSL1, TRIP5
Swiss Prot
P52732 Human, Q6P9P6 Mouse, F1MAB8 Rat
Cellular Locus
Cytoplasm, Cytoskeleton.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Eg5 aa 80-257 / 1,056.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell, IHC-P, FC
Positive Control
A431, SH-SY-5Y, SiHa, rat kidney tissue, human lung cancer tissue.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:50;IHC-P: 1:50-1:400;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 119 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Eg5 Rabbit Polyclonal Antibody?

The catalog number for Eg5 Rabbit Polyclonal Antibody is ER1803-25.

What sizes are available for Eg5 Rabbit Polyclonal Antibody?

Eg5 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Eg5 Rabbit Polyclonal Antibody in stock?

Eg5 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Eg5 Rabbit Polyclonal Antibody used for?

Eukaryotes contain a superfamily of microtubule-based motor proteins comprising kinesin and a number of related proteins that are thought to participate in various forms of intracellular motility, including cell division and organelle transport. KIF11 (also known as kinesin family member 11, Eg5 or

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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