Fusion glycoprotein F0 Rabbit Polyclonal Antibody

About this product

During virus entry, induces fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2. Interacts directly with heparan sulfate and may participate in virus attachment. Furthermore, the F2 subunit was identifed as the major determinant of RSV host cell specificity. Later in infection, proteins F expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis. The fusion protein is also able to trigger p53-dependent apoptosis.

Specifications

Catalog number

ER1803-51

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

Fusion glycoprotein F0 antibody Fusion glycoprotein F1 antibody Fusion glycoprotein F2 antibody Fusion protein (F) antibody RSV fusion protein antibody

Abbreviation

F

Swiss Prot

W8CLH7 Avian avulavirus 1

Host

Rabbit

Species Reactivity

Avian avulavirus 1

Immunogen

Synthetic peptide within newcastle disease virus Fusion glycoprotein F0 aa 504-553 / 553.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, ELISA

Positive Control

Fusion glycoprotein F0 transfected HEK293 cell.

Concentration

1 mg/mL

Dilution

WB: 1:500-1,000 ;ELISA: 1:5,000-1:10,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 59 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No