CD40 Rabbit Polyclonal Antibody

About this product

Resting B cells can be activated and clonally expanded into antibody-producing cells in response to a combination of cell contact and soluble signals provided by primed helper T (Th) cells. A receptor ligand pair central to the trans-mission of this signal is CD40, expressed on the surface of B cells, together with CD40L, expressed on activated T cells. In the presence of such stimulus, IL-4 and IL-13 are capable of triggering immunoglobulin class switching and secretion of IgE. B cells are sensitive to these cytokines only subsequent to CD40/CD40L-driven DNA synthesis. A downstream mediator of the CD40 signaling pathway, designated CRAF, is a member of an expanding family of proteins that contain a conserved cysteine- and histidine-rich RING finger motif.

Specifications

Catalog number

ER1803-54

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

AI326936 antibody B cell associated molecule CD40 antibody B cell surface antigen CD40 antibody B cell-associated molecule antibody B-cell surface antigen CD40 antibody Bp50 antibody CD 40 antibody CD40 antibody CD40 antigen (TNF receptor superfamily member 5) antibody CD40 antigen antibody CD40 molecule antibody CD40 molecule, TNF receptor superfamily member 5 antibody CD40 protein antibody CD40 type II isoform antibody CD40L receptor antibody CDw40 antibody GP39 antibody HIGM1 antibody IGM antibody IMD3 antibody MGC9013 antibody Nerve growth factor receptor related B lymphocyte activation molecule antibody OTTHUMP00000031699 antibody OTTHUMP00000031700 antibody p50 antibody T-BAM antibody TBAM antibody TNF receptor superfamily member 5 antibody TNFRSF5 antibody TNR5_HUMAN antibody TRAP antibody Tumor necrosis factor receptor superfamily , member 5 antibody Tumor necrosis factor receptor superfamily member 5 antibody Tumor necrosis factor receptor superfamily member 5 precursor antibody Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody

Abbreviation

CD40, TNFRSF5

Swiss Prot

P25942 Human, P27512 Mouse,

Cellular Locus

Plasma membrane. Secreted.

Host

Rabbit

Species Reactivity

Human, Rat, Mouse

Immunogen

Recombinant protein within Human CD40 aa 1-213 / 277.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Daudi cell lysates, SiHa, rat spleen tissue, human tonsil tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50 -1:200 ;FC: 1:50-1:100

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 31 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No