SEL1L Rabbit Polyclonal Antibody — image 1 of 3

Product details

SEL1L Rabbit Polyclonal Antibody

Catalog number ER1803-69

Price for ER1803-69

Size / count 100 µL

About this product

Protein sel-1 homolog 1 is a protein that in humans is encoded by the SEL1L gene. May play a role in Notch signaling. May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. In mammals, the most well-characterized ERAD machinery is the highly conserved complex of suppressor-enhancer of lin-12–like and hydroxymethylglutaryl-CoA reductase degradation protein 1 (SEL1L-HRD1), which consists of the E3 ubiquitin ligase HRD1 and its adaptor protein SEL1Lc.The Sel1L-deficient experimental model of central diabetes insipidus is unlikely to be observed in humans, as Sel1L loss is embryonically lethal. Three-week-old mice with Sel1L deficiency specifically in AVP neurons (Sel1LAVP mice) lacked AVP-positive transport vesicles in axons, a phenotype that explains the development of the central diabetes insipidus phenotype in these mice.

Specifications

Catalog number: ER1803-69
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: IBD2 antibody PRO1063 antibody Protein sel-1 homolog 1 antibody SE1L1_HUMAN antibody Sel 1 like protein antibody Sel 1 suppressor of lin 12 like antibody Sel-1L antibody SEL1 LIKE antibody Sel1l antibody SEL1LIKE antibody Suppressor of lin-12-like protein 1 antibody TSA305 antibody UNQ128 antibody UNQ128/PRO1063 antibody
Abbreviation: Gtsf1, 56699
Swiss Prot: Q5RIK6 Zebrafish
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Zebrafish
Immunogen: Recombinant protein within zebrafish SEL1L aa 109-281 / 776.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Tissue, IHC-P
Positive Control: Zebrafish lysate, Zebrafish.
Concentration: 1 mg/mL
Dilution: WB: 1:500;IF-Tissue:1:50-1:200;IHC-P:1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 86 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for SEL1L Rabbit Polyclonal Antibody?

The catalog number for SEL1L Rabbit Polyclonal Antibody is ER1803-69.

What sizes are available for SEL1L Rabbit Polyclonal Antibody?

SEL1L Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is SEL1L Rabbit Polyclonal Antibody in stock?

SEL1L Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is SEL1L Rabbit Polyclonal Antibody used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.