Rad21 Rabbit Polyclonal Antibody — image 1 of 3

Product details

Rad21 Rabbit Polyclonal Antibody

Catalog number ER1803-73

Price for ER1803-73

Size / count 100 µL

About this product

Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.

Specifications

Catalog number: ER1803-73
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CDLS4 antibody Double-strand-break repair protein rad21 homolog antibody hHR21 antibody HR21 antibody HRAD21 antibody KIAA0078 antibody MCD1 antibody Nuclear matrix protein 1 antibody NXP-1 antibody NXP1 antibody Protein involved in DNA double-strand break repair antibody RAD21 antibody RAD21 homolog (S. pombe) antibody RAD21 homolog antibody RAD21_HUMAN antibody Scc1 antibody SCC1 homolog antibody
Abbreviation: hHR21, NXP-1, RAD21, HR21, KIAA0078, NXP1, SCC1
Swiss Prot: O60216 Human, Q61550 Mouse,
Cellular Locus: Centromere, Chromosome, Nucleus, Cytoplasm, Cytoskeleton.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human Rad21 aa 252-456 / 631.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: Mouse ovary tissue lysate, Daudi cell lysate, MG-63, SiHa, SK-Br-3, rat brain tissue, human thyroid gland carcinoma tissue, human colon tissue, mouse testis tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:100-1:400
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 72 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Rad21 Rabbit Polyclonal Antibody?

The catalog number for Rad21 Rabbit Polyclonal Antibody is ER1803-73.

What sizes are available for Rad21 Rabbit Polyclonal Antibody?

Rad21 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Rad21 Rabbit Polyclonal Antibody in stock?

Rad21 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Rad21 Rabbit Polyclonal Antibody used for?

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.