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Product details

CD13 Rabbit Polyclonal Antibody

Catalog number ER1803-74

Price for ER1803-74

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Size / count 100 µL

About this product

CD13, or aminopeptidase N, is a type II transmembrane glycoprotein that is expressed on most cells of Myeloid origin, including monocytes, basophils, eosinophils, neutrophils and Myeloid leukemias. CD13 is also found on certain epithelial cells, fibroblasts and osteoclasts. CD13 acts as a zinc-binding metalloprotease that plays a role in digestion and may function in the inactivation of some regulatory peptides such as enkephalins. CD13 may play a role in the invasion of cancer cells by enhancing their invasive capacity and metastatic behavior. The activity of CD13 can be inactivated using specific inhibitors that evoke apoptosis of CD13-positive cancer cells. Basic fibroblast growth factor (bFGF) expression upregulates CD13 expression in human melanoma cells by activating both the Myeloid and the epithelial CD13 promoter.

Specifications

Catalog number
ER1803-74
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Alanyl (membrane) aminopeptidase antibody Alanyl aminopeptidase antibody Aminopeptidase M antibody Aminopeptidase N antibody AMPN_HUMAN antibody ANPEP antibody AP M antibody AP N antibody AP-M antibody AP-N antibody APN antibody CD 13 antibody CD13 antibody CD13 antigen antibody gp150 antibody hAPN antibody LAP 1 antibody LAP1 antibody Microsomal aminopeptidase antibody Myeloid plasma membrane glycoprotein CD13 antibody p150 antibody PEPN antibody
Abbreviation
AP-N, hAPN, AP-M, CD13, ANPEP, APN, CD13, PEPN
Swiss Prot
P15144 Human, P97449 Mouse, P15684 Rat
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human CD13 aa 273-448 / 967.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Rat kidney tissue lysate, Hela liver tissue lysate, HT-29, A549, rat kdiney tissue, human liver tissue, human prostate cancer tissue, human kidney tissue, mouse colon tissue, mouse kidney tissue.
Concentration
1 mg/mL
Dilution
WB:1:500;IF-Cell:1:100-1:400;IHC-P:1:50-1:600;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 110 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for CD13 Rabbit Polyclonal Antibody?

The catalog number for CD13 Rabbit Polyclonal Antibody is ER1803-74.

What sizes are available for CD13 Rabbit Polyclonal Antibody?

CD13 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is CD13 Rabbit Polyclonal Antibody in stock?

CD13 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD13 Rabbit Polyclonal Antibody used for?

CD13, or aminopeptidase N, is a type II transmembrane glycoprotein that is expressed on most cells of Myeloid origin, including monocytes, basophils, eosinophils, neutrophils and Myeloid leukemias. CD13 is also found on certain epithelial cells, fibroblasts and osteoclasts. CD13 acts as a zinc-bindi

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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