Mesothelin Rabbit Polyclonal Antibody — image 1 of 3

Product details

Mesothelin Rabbit Polyclonal Antibody

Catalog number ER1803-76

Price for ER1803-76

Size / count 100 µL

About this product

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. Mesothelin is over expressed in several human tumors, including mesothelioma, ovarian cancer, pancreatic adenocarcinoma and cholangiocarcinoma. The interaction between mesothelin and MUC16 (also known as CA125) may facilitate the implantation and peritoneal spread of tumors by cell adhesion. Dr. Mitchell Ho and colleagues at the National Cancer Institute identified the region (residues 296-359) consisting of 64 amino acids at the N-terminus of cell surface mesothelin as the functional binding domain for MUC16.

Specifications

Catalog number: ER1803-76
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CAK 1 antibody CAK1 antibody CAK1 antigen antibody cleaved form antibody Megakaryocyte potentiating factor antibody Mesothelin antibody Mesothelin isoform 1 precursor antibody MPF antibody Msln antibody MSLN_HUMAN antibody Pre pro megakaryocyte potentiating factor antibody Pre-pro-megakaryocyte-potentiating factor antibody SMR antibody SMRP antibody Soluble MPF mesothelin related protein antibody
Abbreviation: MPF, MSLN, MPF
Swiss Prot: Q13421 Human
Cellular Locus: Cell membrane, Golgi apparatus, Membrane, Secreted.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human Mesothelin aa 220-410.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: Human tonsil tissue, human lung cancer tissue, SiHa.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:2,000;IF-Cell:1:50;IHC-P:1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 69 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Mesothelin Rabbit Polyclonal Antibody?

The catalog number for Mesothelin Rabbit Polyclonal Antibody is ER1803-76.

What sizes are available for Mesothelin Rabbit Polyclonal Antibody?

Mesothelin Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Mesothelin Rabbit Polyclonal Antibody in stock?

Mesothelin Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mesothelin Rabbit Polyclonal Antibody used for?

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.