RYR3 Rabbit Polyclonal Antibody

About this product

The protein encoded by this gene is a ryanodine receptor, which functions to release calcium from intracellular storage for use in many cellular processes. For example, the encoded protein is involved in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum followed by depolarization of T-tubules. Two transcript variants encoding different isoforms have been found for this gene. Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca2+ release by other calcium channels. Calcium channel that mediates Ca2+-induced Ca2+ release from the endoplasmic reticulum in non-muscle cells. Contributes to cellular calcium ion homeostasis (By similarity). Plays a role in cellular calcium signaling.

Specifications

Catalog number

ER1803-92

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

Brain ryanodine receptor-calcium release channel Brain-type ryanodine receptor Type 3 ryanodine receptor Ryanodine receptor 3 Brain ryanodine receptor calcium release channel antibody Brain type ryanodine receptor antibody Cardiac muscle ryanodine receptor calcium release channel antibody Cardiac muscle type ryanodine receptor antibody CCO antibody Central core disease of muscle antibody HBRR antibody MHS antibody Ryanodine receptor 3 antibody Ryanodine receptor type1 antibody RYDR antibody RYR 3 antibody RYR antibody RYR3 antibody Sarcoplasmic reticulum calcium release channel antibody Skeletal muscle calcium release channel antibody Skeletal muscle ryanodine receptor antibody Skeletal muscle type ryanodine receptor antibody Skeletal muscle-type ryanodine receptor antibody SKRR antibody VTSIP antibody

Abbreviation

RYR-3, RyR3, HBRR

Swiss Prot

Q15413 Human, Q14AQ9 Mouse,

Cellular Locus

Endoplasmic reticulum, Membrane, Sarcoplasmic reticulum.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human RYR3 aa 1-140 / 4,870.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

Dot Blot, IHC-P, IF-Cell, ELISA

Positive Control

Lovo, rat brain tissue, human kidney tissue, human placenta tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

ELISA:1:5,000-1:10,000;Dot Blot:1:2000-1:20,000;IF-Cell:1:100;IHC-P:1:50-1:200

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

552 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No