Connexin 45 / GJA7 / Cx45 Rabbit Polyclonal Antibody — image 1 of 3

Product details

Connexin 45 / GJA7 / Cx45 Rabbit Polyclonal Antibody

Catalog number ER1803-93

Price for ER1803-93

Size / count 100 µL

About this product

Gap junction gamma-1 protein (GJC1), also known as gap junction alpha-7 protein (GJA7) and connexin 45 (Cx45) — is a protein that in humans is encoded by the GJC1 gene. Cx45 is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. GJs consist of 3 major connexin (Cx) isoforms—Cx43, Cx40, and Cx45—each of which are characterized by chamber-specific regional distribution and permeation properties. Cx45 is strongly expressed in the early embryonic myocardium and is required for cardiac development (1). Homozygous Cx45-deficient mice are embryonic lethal; however, in the adult heart, Cx45 is expressed mainly at the SA and AV nodes and is not essential for survival of adult mice. Disease-causing mutations in GJ gamma-1 protein (GJC1), which encodes Cx45, have not yet been identified.

Specifications

Catalog number: ER1803-93
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Connexin 45 / GJA7 antibody Connexin 45 antibody Connexin-45 antibody Connexin45 antibody CX 31.9 antibody CX 45 antibody CX31.9 antibody Cx45 antibody CXG1_HUMAN antibody DKFZp686P0738 antibody Gap junction alpha 7 protein antibody Gap junction alpha-7 protein antibody Gap junction gamma 1 protein antibody Gap junction gamma-1 protein antibody Gap junction protein alpha 7 45kDa antibody Gap junction protein alpha 7 antibody Gap junction protein, gamma 1, 45kDa antibody GJA 7 antibody GJA7 antibody GJC1 antibody GJD3 antibody
Abbreviation: Cx45, GJC1, GJA7
Swiss Prot: P36383 Human, P28229 Mouse, A4GG66 Rat
Cellular Locus: Cell membrane, Gap junction.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human Connexin 45 aa 257-396 / 396.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: SH-SY5Y, A431, rat uterus tissue, human liver cancer tissue, human kidney tissue, human placenta tissue.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:1000 ;IF-Cell:1:500-1:100 ;IHC-P:1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 45 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Connexin 45 / GJA7 / Cx45 Rabbit Polyclonal Antibody?

The catalog number for Connexin 45 / GJA7 / Cx45 Rabbit Polyclonal Antibody is ER1803-93.

What sizes are available for Connexin 45 / GJA7 / Cx45 Rabbit Polyclonal Antibody?

Connexin 45 / GJA7 / Cx45 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Connexin 45 / GJA7 / Cx45 Rabbit Polyclonal Antibody in stock?

Connexin 45 / GJA7 / Cx45 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Connexin 45 / GJA7 / Cx45 Rabbit Polyclonal Antibody used for?

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.