Cytokeratin 17 Rabbit Polyclonal Antibody — image 1 of 3

Product details

Cytokeratin 17 Rabbit Polyclonal Antibody

Catalog number ER1803-94

Price for ER1803-94

Size / count 100 µL

About this product

Cytokeratin 17 is a member of the Cytokeratin subfamily of intermediate filament proteins (IFPs). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Cytokeratin 17 contains 432 amino acids and is expressed in the nail bed, hair follicle, sebaceous glands and other epidermal appendages. Cytokeratin 17 functions to regulate cell growth and size through its interactions with the adaptor protein 14-3-3-sigma to mediate protein synthesis. Mutations in the gene encoding for Cytokeratin 17 lead to depressed protein translation and smaller sized skin keratinocytes, corresponding to decreased Akt/mTOR signaling activity. Cytokeratin 17 may be a useful marker for cervical stem cell identification, squamous cell carcinoma of the larynx, respiratory syncytial virus and transitional cell carcinomas of the human urinary tract.

Specifications

Catalog number: ER1803-94
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 39.1 antibody CK 17 antibody CK17 antibody CK-17 antibody Cytokeratin-17 antibody K17 antibody K1C17_HUMAN antibody Keratin 17 antibody keratin 17 epitope S1 antibody keratin 17 epitope S2 antibody keratin 17 epitope S4 antibody Keratin 17, type I antibody Keratin antibody Keratin type I cytoskeletal 17 antibody keratin, type i cytoskeletal 17 [version 1] antibody Keratin-17 antibody KRT17 antibody PC antibody PC2 antibody PCHC1 antibody type I cytoskeletal 17 antibody
Abbreviation: CK-17, K17
Swiss Prot: Q04695 Human, Q9QWL7 Mouse, Q6IFU8 Rat
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human Cytokeratin 17 aa 100-300.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: A431, SiHa, rat prostate tissue, human tonsil tissue, human lung cancer tissue, human breast tissue, mouse skin tissue.
Concentration: 1 mg/mL
Dilution: WB:1:1,000-1:5000 ;IHC-P:1:100-1:500 ;FC:1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 48 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Cytokeratin 17 Rabbit Polyclonal Antibody?

The catalog number for Cytokeratin 17 Rabbit Polyclonal Antibody is ER1803-94.

What sizes are available for Cytokeratin 17 Rabbit Polyclonal Antibody?

Cytokeratin 17 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Cytokeratin 17 Rabbit Polyclonal Antibody in stock?

Cytokeratin 17 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cytokeratin 17 Rabbit Polyclonal Antibody used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.