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Product details

Kir6.2 Rabbit Polyclonal Antibody

Catalog number ER1803-98

Price for ER1803-98

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Size / count 100 µL

About this product

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow Potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive Disfect characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple Alternative spliced ​​transcript variants that encode different protein isoforms have been described for this gene.

Specifications

Catalog number
ER1803-98
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
ATP sensitive inward rectifier potassium channel 11 antibody Beta cell inward rectifier subunit antibody BIR antibody HHF 2 antibody HHF2 antibody IKATP antibody Inward rectifier K (+) channel Kir6.2 antibody Inwardly rectifying potassium channel KIR6.2 antibody IRK 11 antibody IRK11 antibody KCNJ11 antibody Kir 6.2 antibody Kir6.2 antibody MGC133230 antibody PHHI antibody Potassium channel inwardly rectifing subfamily J member 11 antibody Potassium channel, inwardly rectifying subfamily J member 11 antibody Potassium inwardly rectifying channel J11 antibody TNDM 3 antibody TNDM3 antibody
Abbreviation
KCNJ11
Swiss Prot
Q14654 Human, Q61743 Mouse, P70673 Rat
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Kir62 aa 184-323 / 390.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Human liver tissue lysate, mouse liver tissue lysate, A375, PC-3M, mouse liver tissue, mouse pancreas tissue, human prostate cancer tissue.
Concentration
1 mg/mL
Dilution
WB:1:500-1:1,000 ;IF-Cell:1:50-1:200 ;IHC-P:1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Kir6.2 Rabbit Polyclonal Antibody?

The catalog number for Kir6.2 Rabbit Polyclonal Antibody is ER1803-98.

What sizes are available for Kir6.2 Rabbit Polyclonal Antibody?

Kir6.2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Kir6.2 Rabbit Polyclonal Antibody in stock?

Kir6.2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Kir6.2 Rabbit Polyclonal Antibody used for?

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow Potassium

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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