CBARA1 Rabbit Polyclonal Antibody

Catalog number ER1803-99

Price for ER1803-99

Size / count 100 µL

About this product

Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains. MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptake. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Acts as a gatekeeper of MCU at low concentration of calcium, preventing channel opening. Enhances MCU opening at high calcium concentration, allowing a rapid response of mitochondria to calcium signals generated in the cytoplasm. Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake. Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

Catalog number: ER1803-99
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Allergen Hom s 4 antibody ara CALC antibody atopy related autoantigen antibody atopy related autoantigen CALC antibody Atopy-related autoantigen CALC antibody CALC antibody calcium binding atopy related autoantigen 1 antibody Calcium uptake protein 1 antibody calcium uptake protein 1, mitochondrial antibody Calcium-binding atopy-related autoantigen 1 antibody CBARA1 antibody EFHA3 antibody FLJ12684 antibody MICU1 antibody MICU1_HUMAN antibody mitochondrial antibody mitochondrial calcium uptake 1 antibody MPXPS antibody
Abbreviation: ara CALC, MICU1, CALC, CBARA1
Swiss Prot: Q9BPX6 Human, Q8VCX5 Mouse, Q6P6Q9 Rat
Cellular Locus: Mitochondrion.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human CBARA1 aa 14-154 / 476.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB
Positive Control: Mouse kidney tissue, rat brain tissue, Hela.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:2,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 54 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CBARA1 Rabbit Polyclonal Antibody?

The catalog number for CBARA1 Rabbit Polyclonal Antibody is ER1803-99.

What sizes are available for CBARA1 Rabbit Polyclonal Antibody?

CBARA1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is CBARA1 Rabbit Polyclonal Antibody in stock?

CBARA1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is CBARA1 Rabbit Polyclonal Antibody used for?

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.