CD163 Rabbit Polyclonal Antibody — image 1 of 3

Product details

CD163 Rabbit Polyclonal Antibody

Catalog number ER1804-03

Price for ER1804-03

Size / count 100 µL

About this product

CD163, also designated M130, is a macrophage-associated antigen that is a member of the scavenger receptor cysteine-rich (SRCR) superfamily. It is highly expressed on macrogphages and to a lesser extent on monocytes. The acute phase-regulated and signal-inducing macrophage protein, CD163, is a receptor that scavenges hemoglobin by mediating endocytosis of haptoglobin-hemoglobin complexes. CD163 binds only haptoglobin and hemoglobin in complex, which indicates the exposure of a receptor-binding neoepitope. The receptor-ligand interaction is calcium-dependent and of high affinity. The existence of several CD163 isoforms, which differ in the structure of their cytoplasmic domains and putative phosphorylation sites, suggests that these isoforms also differ in their signaling mechanism. The gene which encodes CD163 maps to human chromosome 12p13.31.

Specifications

Catalog number: ER1804-03
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: C163A_HUMAN antibody CD 163 antibody CD163 antibody CD163 antigen antibody CD163 molecule antibody Hemoglobin scavenger receptor antibody M130 antibody M130 antigen precursor antibody Macrophage associated antigen antibody MM130 antibody OTTHUMP00000238617 antibody OTTHUMP00000238618 antibody OTTHUMP00000238619 antibody OTTHUMP00000238620 antibody SCARI1 antibody Scavenger receptor cysteine rich type 1 protein M130 antibody sCD163 antibody Soluble CD163 antibody
Abbreviation: sCD163, CD163, M130
Swiss Prot: Q86VB7 Human, Q2VLH6 Mouse, A0A8I5ZQF0 Rat
Cellular Locus: Secreted, Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human aa 22-161 / 1,156.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, IF-Cell
Positive Control: Human lung tissue lysate, human liver tissue lysate, LOVO, SH-SY5Y, Siha, A431, mouse liver tissue, rat lung tissue, human placenta tissue.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:1,000 ;IF-Cell:1:50-1:200 ;IHC-P:1:50-1:600
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 125 kDa, observed band size: 150 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CD163 Rabbit Polyclonal Antibody?

The catalog number for CD163 Rabbit Polyclonal Antibody is ER1804-03.

What sizes are available for CD163 Rabbit Polyclonal Antibody?

CD163 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is CD163 Rabbit Polyclonal Antibody in stock?

CD163 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD163 Rabbit Polyclonal Antibody used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.