RBPMS Guinea Pig Polyclonal Antibody

Catalog number ER1901-06

Price for ER1901-06

Size / count 100 µL

About this product

This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly (A) RNA.

Specifications

Catalog number: ER1901-06
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: RNA-binding protein with multiple splicing Heart and RRM expressed sequence
Abbreviation: RBP-MS, Hermes, RBPMS, HERMES
Swiss Prot: Q93062 Human, Q9WVB0 Mouse
Cellular Locus: Cytoplasm. Nucleus.
Host: Guinea Pig
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within human RBPMS 1-30 conjugated to Keyhole Limpet Haemocyanin.
Isotype: IgG
Conjugation: Non-conjugated
Type: Guinea Pig polyclonal Antibody
Applications: WB, ELISA
Positive Control: Ubiquitously expressed, at various levels depending on the isoform and the tissue.
Concentration: 1 mg/mL
Dilution: ELISA:1:1,000-1:5,000;WB: 1:500-1:1,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 21 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

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