TRPML3 Rabbit Polyclonal Antibody — image 1 of 3

Product details

TRPML3 Rabbit Polyclonal Antibody

Catalog number ER1901-21

Price for ER1901-21

Size / count 100 µL

About this product

Nonselective ligand-gated cation channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca2+-permeable cation channel with inwardly rectifying activity. Mediates release of Ca2+ from endosomes to the cytoplasm, contributes to endosomal acidification and is involved in the regulation of membrane trafficking and fusion in the endosomal pathway (By similarity). Does not seem to act as mechanosensory transduction channel in inner ear sensory hair cells. Proposed to play a critical role at the cochlear stereocilia ankle-link region during hair-bundle growth. Involved in the regulation of autophagy. Through association with GABARAPL2 may be involved in autophagosome formation possibly providing Ca2+ for the fusion process. Through a possible and probably tissue-specific heteromerization with MCOLN1 may be at least in part involved in many lysosome-dependent cellular events. Possible heteromeric ion channel assemblies with TRPV5 show pharmacological similarity with TRPML3 (By similarity).

Specifications

Catalog number: ER1901-21
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: MCOLN 3 antibody MCOLN3 antibody FLJ11006 antibody FLJ36629 antibody MCLN3_HUMAN antibody Mcoln3 antibody MGC71509 antibody Mucolipin 3 antibody Mucolipin-3 antibody TRP ML3 antibody TRPML3 antibody
Abbreviation: Mcoln3
Swiss Prot: Q8TDD5 Human, Q8R4F0 Mouse,
Cellular Locus: Early endosome membran, late endosome membrane, stereocilium membrane, autophagosome membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human TRPML3 aa 504-553 / 553.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: A549 cell lysate, HL-60 cell lysate, HEK-293 cell lysate, mouse brain tissue lysate, mouse kidney tissue lysate, rat brain tissue lysate, rat kidney tissue lysate, human liver carcinoma tissue, F9.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:2,000 ;IF-Cell:1:50 ;IHC-P:50-1:200 ;FC:1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 64 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for TRPML3 Rabbit Polyclonal Antibody?

The catalog number for TRPML3 Rabbit Polyclonal Antibody is ER1901-21.

What sizes are available for TRPML3 Rabbit Polyclonal Antibody?

TRPML3 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is TRPML3 Rabbit Polyclonal Antibody in stock?

TRPML3 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is TRPML3 Rabbit Polyclonal Antibody used for?

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.