DOG1 Rabbit Polyclonal Antibody — image 1 of 3

Product details

DOG1 Rabbit Polyclonal Antibody

Catalog number ER1901-30

Price for ER1901-30

Size / count 100 µL

About this product

ANO1 (anoctamin 1), also known as DOG1, ORAOV2, TAOS2 or TMEM16A, is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in liver, gastrointestinal muscle and skeletal muscle, ANO1 functions as a calcium-activated chloride channel that is required for normal tracheal development. Human ANO1 shares 90% sequence identity with its mouse counterpart, suggesting a conserved role between species. ANO1 is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for ANO1 in carcinogenesis. Three isoforms of ANO1 exist due to alternative splicing events.

Specifications

Catalog number: ER1901-30
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: ANO 1 antibody ANO1 antibody ANO1_HUMAN antibody Anoctamin 1 antibody Anoctamin 1 calcium activated chloride channel antibody Anoctamin-1 antibody Anoctamin1 antibody Ca2+ activated Cl- channel antibody Calcium Activated Chloride Channel antibody Discovered on gastrointestinal stromal tumors protein 1 antibody DOG 1 antibody DOG1 antibody FLJ10261 antibody Membrane protein antibody Oral cancer overexpressed 2 antibody Oral cancer overexpressed protein 2 antibody ORAOV 2 antibody ORAOV2 antibody TAOS 2 antibody TAOS2 antibody TMEM 16A antibody TMEM16A antibody Transmembrane protein 16A (eight membrane spanning domains) antibody Transmembrane protein 16A antibody Tumor amplified and overexpressed sequence 2 antibody Tumor-amplified and overexpressed sequence 2 antibody
Abbreviation: ANO1
Swiss Prot: Q5XXA6 Human
Cellular Locus: Cell membrane, cytoplasm.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within C-terminal human DOG1.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: PC-3M cell lysates, A549, HepG2, human liver carcinoma tissue, human seminal pouch tissue.
Concentration: 1mg/mL
Dilution: WB:1:500-1:1000 ;IF-Cell:1:50-1:200 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 114/97 kDa (Predicted band size)
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for DOG1 Rabbit Polyclonal Antibody?

The catalog number for DOG1 Rabbit Polyclonal Antibody is ER1901-30.

What sizes are available for DOG1 Rabbit Polyclonal Antibody?

DOG1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is DOG1 Rabbit Polyclonal Antibody in stock?

DOG1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is DOG1 Rabbit Polyclonal Antibody used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.