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Product details

BIN1 Rabbit Polyclonal Antibody

Catalog number ER1901-39

Price for ER1901-39

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Size / count 100 µL

About this product

Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling. Is a negative regulator of endocytosis (By similarity). Is also involved in the regulation of intracellular vesicles sorting, modulation of BACE1 trafficking and the control of amyloid-beta production. In neuronal circuits, endocytosis regulation may influence the internalization of PHF-tau aggregates (By similarity). May be involved in the regulation of MYC activity and the control cell proliferation. Has actin bundling activity and stabilizes actin filaments against depolymerization in vitro.

Specifications

Catalog number
ER1901-39
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
AMPH 2 antibody AMPH2 antibody Amphiphysin 2 antibody Amphiphysin II antibody Amphiphysin like protein antibody amphiphysin-like antibody Amphiphysin-like protein antibody AMPHL antibody Bin1 antibody BIN1_HUMAN antibody Box Dependant MYC Interacting Protein 1 antibody Box-dependent myc-interacting protein 1 antibody Bridging integrator 1 antibody DKFZp547F068 antibody MGC10367 antibody MGC105358 antibody Myc box dependent interacting protein 1 antibody Myc box-dependent-interacting protein 1 antibody SH3P9 antibody
Abbreviation
BIN1, AMPHL
Swiss Prot
O00499 Human, O08539 Mouse, O08839 Rat
Cellular Locus
Cell membrane, Cytoplasm, Endosome, Nucleus, Plasma membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human BIN1 aa 56-257 / 593.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Rat spleen tissue lysate, SiHa, rat brain tissue, human colon cancer tissue, human spleen tissue, human kidney tissue, mouse skeletal muscle tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 65 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for BIN1 Rabbit Polyclonal Antibody?

The catalog number for BIN1 Rabbit Polyclonal Antibody is ER1901-39.

What sizes are available for BIN1 Rabbit Polyclonal Antibody?

BIN1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is BIN1 Rabbit Polyclonal Antibody in stock?

BIN1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is BIN1 Rabbit Polyclonal Antibody used for?

Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling. Is a negative regulator of endocytosis (B

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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