KCNK18 Rabbit Polyclonal Antibody — image 1 of 3

Product details

KCNK18 Rabbit Polyclonal Antibody

Catalog number ER1901-46

Price for ER1901-46

Size / count 100 µL

About this product

Outward rectifying potassium channel. Produces rapidly activating outward rectifier K+ currents. May function as background potassium channel that sets the resting membrane potential. Channel activity is directly activated by calcium signal. Activated by the G (q)-protein coupled receptor pathway. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensory function with special respect to pain sensation.

Specifications

Catalog number: ER1901-46
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: K2p18.1 antibody KCNK18 antibody KCNKI_HUMAN antibody MGR13 antibody OTTHUMP00000020575 antibody Potassium channel subfamily K member 18 antibody TRESK 2 antibody TRESK antibody TRESK2 antibody TRIK antibody TWIK related individual K+ channel antibody TWIK related individual potassium channel antibody TWIK related spinal cord K+ channel antibody TWIK related spinal cord potassium channel antibody TWIK-related individual potassium channel antibody TWIK-related spinal cord potassium channel antibody
Abbreviation: Kcnk18
Swiss Prot: Q7Z418 Human, Q6VV64 Mouse, Q6Q1P3 Rat
Cellular Locus: Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within mouse KCNK18 aa 44-93 / 394.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Rat spinal cord tissue lysates, N2A, SHG-44, rat spinal cord tissue, mouse skeletal muscle tissue, mouse brain tissue, SH-SY5Y.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:2,000;IF-Cell:1:50-1:100;IHC-P:1:100-1:500;FC:1:100-1:500
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 44 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for KCNK18 Rabbit Polyclonal Antibody?

The catalog number for KCNK18 Rabbit Polyclonal Antibody is ER1901-46.

What sizes are available for KCNK18 Rabbit Polyclonal Antibody?

KCNK18 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is KCNK18 Rabbit Polyclonal Antibody in stock?

KCNK18 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is KCNK18 Rabbit Polyclonal Antibody used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.