ZAC Rabbit Polyclonal Antibody

About this product

Zinc-activated ion channel (ZAC), is a human protein encoded by the ZACN gene. ZAC forms a cation-permeable ligand-gated ion channel of the "Cys-loop" superfamily. The ZAC gene is present in humans and dogs, but no ortholog is thought to exist in the rat or mouse genomes. ZAC mRNA is expressed in prostate, thyroid, trachea, lung, brain (adult and fetal), spinal cord, skeletal muscle, heart, placenta, pancreas, liver, kidney and stomach. The endogenous ligand for ZAC is thought to be Zn2+, although ZAC has also been found to activate spontaneously. The function of spontaneous ZAC activation is unknown.

Specifications

Catalog number

ER1901-48

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

Zinc-activated ligand-gated ion channel Ligand-gated ion channel zinc-activated 1 Ligand-gated ion-channel receptor L2 L2 LGICZ LGICZ1 ZAC

Abbreviation

ZACN

Swiss Prot

Q401N2 Human

Cellular Locus

Cell membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human ZAC aa 139-188 / 412.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

Human kidney tissue lysate, HepG2 cell lysate, N2A, SiHa, rat brain tissue, human liver tissue, human kidney tissue.

Concentration

1 mg/mL

Dilution

WB:1:500-1:2,000;IF-Cell:1:50-1:100;IHC-P:1:50-1:200

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 46 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No