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Product details

KV2.2 Rabbit Polyclonal Antibody

Catalog number ER1901-55

Price for ER1901-55

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Size / count 100 µL

About this product

Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and smooth muscle cells. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient. Homotetrameric channels mediate a delayed-rectifier voltage-dependent outward potassium current that display rapid activation and slow inactivation in response to membrane depolarization. Can form functional homotetrameric and heterotetrameric channels that contain variable proportions of KCNB1; channel properties depend on the type of alpha subunits that are part of the channel . Can also form functional heterotetrameric channels with other alpha subunits that are non-conducting when expressed alone, such as KCNS1 and KCNS2, creating a functionally diverse range of channel complexes. In vivo, membranes probably contain a mixture of heteromeric potassium channel complexes, making it difficult to assign currents observed in intact tissues to any particular potassium channel family member. Contributes to the delayed-rectifier voltage-gated potassium current in cortical pyramidal neurons and smooth muscle cells

Specifications

Catalog number
ER1901-55
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
delayed rectifier potassium channel protein antibody KCNB2 antibody KCNB2_HUMAN antibody potassium channel Kv2.2 antibody potassium voltage gated channel subfamily B member 2 antibody Potassium voltage-gated channel subfamily B member 2 antibody Voltage-gated potassium channel subunit Kv2.2 antibody
Abbreviation
Kcnb2
Swiss Prot
Q92953 Human, Q63099 Rat
Cellular Locus
Cell membrane, perikaryon, dendrite.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Synthetic peptide within rat KV22 aa 842-891 / 907.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
SH-SY5Y cell lysates, rat brain tissue, rat smooth muscle tissue, A431.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:1,000 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 103 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for KV2.2 Rabbit Polyclonal Antibody?

The catalog number for KV2.2 Rabbit Polyclonal Antibody is ER1901-55.

What sizes are available for KV2.2 Rabbit Polyclonal Antibody?

KV2.2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is KV2.2 Rabbit Polyclonal Antibody in stock?

KV2.2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is KV2.2 Rabbit Polyclonal Antibody used for?

Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and smooth muscle cells. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemic

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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