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Product details

GABRA4 Rabbit Polyclonal Antibody

Catalog number ER1901-60

Price for ER1901-60

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Size / count 100 µL

About this product

Gamma-aminobutyric acid receptor subunit alpha-4 is a protein that in humans is encoded by the GABRA4 gene. Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.

Specifications

Catalog number
ER1901-60
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
GABA (A) receptor subunit alpha 4 antibody GABA (A) receptor subunit alpha-4 antibody GABR A4 antibody GABRA 4 antibody Gabra4 antibody Gamma aminobutyric acid (GABA) A receptor alpha 4 antibody Gamma aminobutyric acid A receptor alpha 4 antibody Gamma aminobutyric acid receptor alpha 4 subunit antibody Gamma aminobutyric acid receptor subunit alpha 4 antibody Gamma-aminobutyric acid receptor subunit alpha-4 antibody GBRA4_HUMAN antibody
Abbreviation
GABRA4
Swiss Prot
P48169 Human, Q9D6F4 Mouse, P28471 Rat
Cellular Locus
Postsynaptic cell membrane, cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within mouse GABRA4 aa 19-68 / 552.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
SH-SY5Y cell lysates, rat brain tissue, mouse brain tissue, SH-SY5Y.
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000 ;IHC-P:1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size 61 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for GABRA4 Rabbit Polyclonal Antibody?

The catalog number for GABRA4 Rabbit Polyclonal Antibody is ER1901-60.

What sizes are available for GABRA4 Rabbit Polyclonal Antibody?

GABRA4 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is GABRA4 Rabbit Polyclonal Antibody in stock?

GABRA4 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is GABRA4 Rabbit Polyclonal Antibody used for?

Gamma-aminobutyric acid receptor subunit alpha-4 is a protein that in humans is encoded by the GABRA4 gene. Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

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