Histone H2A.x Rabbit Polyclonal Antibody — image 1 of 3

Product details

Histone H2A.x Rabbit Polyclonal Antibody

Catalog number ER1901-70

Price for ER1901-70

Size / count 100 µL

About this product

Histone H2A.X is a member of the Histone H2A family, which is involved in nucleosomal organization of chromatin. The H2AFX gene is located in close proximity to the Porphobilinogen deaminase (PBG-D) gene in both mouse and human, and maps to chromosome 9 and 11q23, respectively. H2A.X differs from the other members of the H2A family by the presence of a highly conserved C-terminal motif. It is rapidly phosphorylated in response to ionizing radiation and plays an important role in the recognition and repair of DNA double stranded breaks. The phosphorylated form of H2A.X, designated γ-H2A.X, forms nuclear foci at the heavy chain constant region of cells involved in class switch recombination (CSR), a region-specific DNA reaction that replaces one immunoglobulin heavy chain constant region gene with another. The phosphorylated γ-H2A.X is also thought to initiate subsequent repair factors, including Rad50, Rad51 and BRCA1.

Specifications

Catalog number: ER1901-70
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: AW228881 antibody H2A histone family member X antibody H2A.FX antibody H2A.X antibody H2a/x antibody H2AFX antibody H2AX antibody H2AX histone antibody H2AX_HUMAN antibody Hist5.2ax antibody Histone 2A antibody Histone 2AX antibody Histone H2A.X antibody Histone H2AX antibody RGD1566119 antibody
Abbreviation: Histone H2AX,H2a/x,Histone H2A.X,H2AFX,
Swiss Prot: P16104 Human, P27661 Mouse
Cellular Locus: Nucleus
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human Histone H2AX aa 1-50 / 143.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, IF-Cell, IF-Tissue, FC
Positive Control: MCF-7 cell lysates, SHSY5Y, Rat testicular tissue, human lung cancer tissue, human liver tissue, mouse fallopian tube tissue.
Concentration: 1mg/mL
Dilution: WB:1:500-1:1000;IHC-P:1:100-1:500;IF-Cell:1:100-1:500;IF-Tissue:1:100-1:500;FC:1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 15 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Histone H2A.x Rabbit Polyclonal Antibody?

The catalog number for Histone H2A.x Rabbit Polyclonal Antibody is ER1901-70.

What sizes are available for Histone H2A.x Rabbit Polyclonal Antibody?

Histone H2A.x Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Histone H2A.x Rabbit Polyclonal Antibody in stock?

Histone H2A.x Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Histone H2A.x Rabbit Polyclonal Antibody used for?

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.