p15 INK4b Rabbit Polyclonal Antibody — image 1 of 3

Product details

p15 INK4b Rabbit Polyclonal Antibody

Catalog number ER1901-75

Price for ER1901-75

Size / count 100 µL

About this product

Cyclin-dependent kinase 4 inhibitor B also known as multiple tumor suppressor 2 (MTS-2) or p15INK4b is a protein that is encoded by the CDKN2B gene in humans. This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, also known as p15Ink4b protein, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases by cyclin D, thus the encoded protein functions as a cell growth regulator that inhibits cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Specifications

Catalog number: ER1901-75
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CDK inhibitory protein antibody CDK4B Inhibitor antibody Cdkn2b antibody CDN2B_HUMAN antibody Cyclin dependent kinase 4 inhibitor B antibody Cyclin Dependent Kinase Inhibitor 2B antibody Cyclin dependent kinase inhibitor 2B p15 inhibits CDK4 antibody Cyclin dependent kinases 4 and 6 binding protein antibody Cyclin-dependent kinase 4 inhibitor B antibody INK4B antibody MTS 2 antibody MTS-2 antibody MTS2 antibody Multiple tumor suppressor 2 antibody Multiple Tumor Supressor 2 antibody OTTHUMP00000021154 antibody OTTHUMP00000021155 antibody p14 CDK inhibitor antibody p14 INK4b antibody p14-INK4b antibody P15 antibody p15 CDK inhibitor antibody p15 inhibits CDK4 antibody p15 INK4b antibody p15-INK4b antibody p15INK4B antibody TP 15 antibody TP15 antibody
Abbreviation: MTS-2, p15INK4B, CDKN2B, MTS2
Swiss Prot: P42772 Human, P55271 Mouse, P55272 Rat
Cellular Locus: Cytoplasm. Also found in the nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human p15 INK4b aa 1-138 / 138.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Hela, SiHa, rat kidney tissue, human esophagus cancer tissue, human small intestine tissue, mouse liver tissue.
Concentration: 1 mg/mL
Dilution: WB:1:500 ;IF-Cell:1:50-1:200 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size 15 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for p15 INK4b Rabbit Polyclonal Antibody?

The catalog number for p15 INK4b Rabbit Polyclonal Antibody is ER1901-75.

What sizes are available for p15 INK4b Rabbit Polyclonal Antibody?

p15 INK4b Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is p15 INK4b Rabbit Polyclonal Antibody in stock?

p15 INK4b Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is p15 INK4b Rabbit Polyclonal Antibody used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.