CACNG2 Rabbit Polyclonal Antibody

About this product

Calcium channel, voltage-dependent, gamma subunit 2, also known as CACNG2 or stargazin is a protein that in humans is encoded by the CACNG2 gene. L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This protein is similar to the mouse stargazin protein, mutations in which having been associated with absence seizures, also known as petit-mal or spike-wave seizures. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family. Stargazin is involved in the transportation of AMPA receptors to the synaptic membrane, and the regulation of their receptor rate constants — via its extracellular domain — once it is there. As it is highly expressed throughout the cerebral cortex, it is likely to have an important role in learning within these areas, due to the importance of AMPA receptors in LTP.

Specifications

Catalog number

ER1901-89

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

AW060990 antibody B230105C07Rik antibody B930041E13Rik antibody Cacng2 antibody Calcium channel voltage dependent gamma subunit 2 antibody CaV gamma 2 antibody CCG2_HUMAN antibody Ipr328 antibody MGC123981 antibody MGC138502 antibody MGC138504 antibody Neuronal voltage gated calcium channel gamma 2 subunit antibody Neuronal voltage-gated calcium channel gamma-2 subunit antibody Stargazer antibody stg antibody TARP gamma-2 antibody Transmembrane AMPAR regulatory protein gamma-2 antibody Voltage dependent calcium channel gamma 2 subunit antibody Voltage-dependent calcium channel gamma-2 subunit antibody Wag antibody Waggler antibody

Abbreviation

Voltage-dependent calcium channel gamma-2 subunit,Neuronal voltage-gated calcium channel gamma-2 subunit,Transmembrane AMPAR regulatory protein gamma-2,TARP gamma-2,CACNG2

Swiss Prot

Q9Y698 Human, O88602 Mouse, Q71RJ2 Rat

Cellular Locus

Cell junction, Membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human CACNG2 aa 196-245 / 323.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, IF-Cell, FC

Positive Control

Mouse cerebellum tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, A549, SHSY5Y, mouse brain tissue, rat Cerebellum tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2000;IHC-P: 1;50-1:200;IF-Cell: 1:50-1:200;FC: 1:50-1:100

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 36 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No