Product details
Catalog number ER1901-99
Price for ER1901-99
Size / count 100 µL
P2X purinoceptor 7 is a protein that in humans is encoded by the P2RX7 gene.The product of this gene belongs to the family of purinoceptors for ATP. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay criteria.The receptor is found in the central and peripheral nervous systems, in microglia, in macrophages, in uterine endometrium, and in the retina. The P2X7 receptor also serves as a pattern recognition receptor for extracellular ATP-mediated apoptotic cell death,regulation of receptor trafficking, mast cell degranulation, and inflammation. Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells
The catalog number for P2X7 Rabbit Polyclonal Antibody is ER1901-99.
P2X7 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.
P2X7 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.
P2X purinoceptor 7 is a protein that in humans is encoded by the P2RX7 gene.The product of this gene belongs to the family of purinoceptors for ATP. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay criteria.T
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The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
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