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Product details

P2X7 Rabbit Polyclonal Antibody

Catalog number ER1901-99

Price for ER1901-99

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Size / count 100 µL

About this product

P2X purinoceptor 7 is a protein that in humans is encoded by the P2RX7 gene.The product of this gene belongs to the family of purinoceptors for ATP. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay criteria.The receptor is found in the central and peripheral nervous systems, in microglia, in macrophages, in uterine endometrium, and in the retina. The P2X7 receptor also serves as a pattern recognition receptor for extracellular ATP-mediated apoptotic cell death,regulation of receptor trafficking, mast cell degranulation, and inflammation. Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells

Specifications

Catalog number
ER1901-99
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
ATP receptor antibody P2rx7 antibody P2RX7_HUMAN antibody P2X purinoceptor 7 antibody P2X7 antibody P2Z receptor antibody Purinergic receptor antibody purinergic receptor P2X, ligand gated ion channel, 7 antibody
Abbreviation
P2X purinoceptor 7,P2X7,ATP receptor,P2Z receptor,Purinergic receptor,P2rx7
Swiss Prot
Q99572 Human, Q9Z1M0 Mouse, Q64663 Rat
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide corresponding to C terminal Rat P2X7.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
SH-SY5Y cell lysate, mouse brain tissue lysate, mouse cerebellum tissue lysate, rat brain tissue lysate, rat brain tissue, human kidney tissue, mouse brain tissue, THP-1.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 69 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for P2X7 Rabbit Polyclonal Antibody?

The catalog number for P2X7 Rabbit Polyclonal Antibody is ER1901-99.

What sizes are available for P2X7 Rabbit Polyclonal Antibody?

P2X7 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is P2X7 Rabbit Polyclonal Antibody in stock?

P2X7 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is P2X7 Rabbit Polyclonal Antibody used for?

P2X purinoceptor 7 is a protein that in humans is encoded by the P2RX7 gene.The product of this gene belongs to the family of purinoceptors for ATP. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay criteria.T

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

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