GSDMC Rabbit Polyclonal Antibody — image 1 of 3

Product details

GSDMC Rabbit Polyclonal Antibody

Catalog number ER1902-22

Price for ER1902-22

Size / count 100 µL

About this product

This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-C, N-terminal) binds to membranes and forms pores, triggering cell death. Pore-forming protein that causes membrane permeabilization and pyroptosis. Released upon cleavage and binds to membrane inner leaflet lipids. Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis. The functional mechanisms and physiological proteases that cleave and activate this pore-forming protein are unknown.

Specifications

Catalog number: ER1902-22
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Gasdermin C antibody Gasdermin-C antibody GSDMC antibody GSDMC_HUMAN antibody Melanoma derived leucine zipper, extra nuclear factor antibody Melanoma-derived leucine zipper-containing extranuclear factor antibody MLZE antibody
Abbreviation: GSDMC
Swiss Prot: Q9BYG8 Human
Cellular Locus: Cell membrane, Cytoplasm, Membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human GSDMC aa 1-220 / 508.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: Human stomach tissue lysates, human lung tissue, human kidney tissue, A549.
Concentration: 1 mg/mL
Dilution: WB:1:1,000-1:2,000 ;IHC-P:1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 58 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for GSDMC Rabbit Polyclonal Antibody?

The catalog number for GSDMC Rabbit Polyclonal Antibody is ER1902-22.

What sizes are available for GSDMC Rabbit Polyclonal Antibody?

GSDMC Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is GSDMC Rabbit Polyclonal Antibody in stock?

GSDMC Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is GSDMC Rabbit Polyclonal Antibody used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.