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Product details

SPATA13 Rabbit Polyclonal Antibody

Catalog number ER1902-32

Price for ER1902-32

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Size / count 100 µL

About this product

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Specifications

Catalog number
ER1902-32
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
APC-stimulated guanine nucleotide exchange factor 2 antibody ARHGEF29 antibody Asef2 antibody FLJ31208 antibody RP11-307N16.3 antibody Spata13 antibody Spermatogenesis-associated protein 13 antibody SPT13_HUMAN antibody
Abbreviation
Spermatogenesis-associated protein 13 APC-stimulated guanine nucleotide exchange factor 2 SPATA13 Asef2
Swiss Prot
Q96N96 Human, Q5DU57 Mouse
Cellular Locus
Cell membrane, Cell projection, Cytoplasm, Membrane.
Host
Rabbit
Species Reactivity
Human, Rat, Mouse
Immunogen
Recombinant protein within Human SPATA13 aa 423-572 / 652.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Rat kidney tissue lysates, rat testis tissue, human colon cancer tissue, human kidney tissue, SHSY5Y.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 75 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for SPATA13 Rabbit Polyclonal Antibody?

The catalog number for SPATA13 Rabbit Polyclonal Antibody is ER1902-32.

What sizes are available for SPATA13 Rabbit Polyclonal Antibody?

SPATA13 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is SPATA13 Rabbit Polyclonal Antibody in stock?

SPATA13 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is SPATA13 Rabbit Polyclonal Antibody used for?

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

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