GATA3 Rabbit Polyclonal Antibody

About this product

GATA3 is a transcription factor that in humans is encoded by the GATA3 gene. Studies in animal models and humans indicate that it controls the expression of a wide range of biologically and clinically important genes. The GATA3 transcription factor is critical for the embryonic development of various tissues as well as for inflammatory and humoral immune responses and the proper functioning of the endothelium of blood vessels. GATA3 haploinsufficiency (i.e. lose of one or the two inherited GATA3 genes) results in a congenital disorder termed the Barakat syndrome. Current clinical and laboratory research is focusing on determining the benefits of directly or indirectly blocking the action of GATA3 in inflammatory and allergic diseases such as asthma. It is also proposed to be a clinically important marker for various types of cancer, particularly those of the breast. However, the role, if any, of GATA3 in the development of these cancers is under study and remains unclear.

Specifications

Catalog number

ER1902-69

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

GATA 3 antibody GATA binding factor 3 antibody GATA binding protein 3 antibody GATA-binding factor 3 antibody Gata3 antibody GATA3_HUMAN antibody HDR antibody HDRS antibody MGC2346 antibody MGC5199 antibody MGC5445 antibody Trans acting T cell specific transcription factor GATA 3 antibody Trans-acting T-cell-specific transcription factor GATA-3 antibody

Abbreviation

GATA3

Swiss Prot

P23771 Human, A0A8I6A6L1 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Rat

Immunogen

Synthetic peptide within human GATA3 aa 1-100.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

SH-SY5Y cell lysates, rat large intestine tissue, MCF-7.

Concentration

1 mg/mL

Dilution

WB:1:500-1:1,000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 48 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No