Rab11-FIP3 Rabbit Polyclonal Antibody

About this product

Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track).

Specifications

Catalog number

ER1902-80

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

EF hands containing Rab interacting protein antibody Eferin antibody Rab11 family interacting protein 3 antibody RAB11FIP3 antibody RFIP3 antibody

Abbreviation

Rab11fip3

Swiss Prot

O75154 Human, Q8CHD8 Mouse

Cellular Locus

Recycling endosome membrane, centrosome, Cleavage furrow, Midbody.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Synthetic peptide within mouse FIP3 aa 543-592 / 1,047.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

MCF-7 cell lysates, mouse liver tissue, mouse kindey tissue.

Concentration

1 mg/mL

Dilution

WB:1:500-1:2,000;IHC-P:1:50-1:200

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size 82/119 kDa.

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No