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Product details
Catalog number ER1902-84
Price for ER1902-84
Size / count 100 µL
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. All members of the Schlafen family contain a conserved core domain and are substantially diversified at the N terminus. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection and its induction leads to G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. Slfn1 and Slfn2 are both unregulated during the double-positive (DP) and single-positive (SP) stages of thymocyte development, whereas Slfn4 is down regulated at these stages. Changes in Schalfen protein expression may contribute to phenotypic differences seen in thymic subsets. Slfn12 (schlafen family member 12), also known as SLFN3, is a 578 amino acid protein belonging to the Schlafen family.
The catalog number for SLFN12 Rabbit Polyclonal Antibody is ER1902-84.
SLFN12 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.
SLFN12 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. All members of the Schlafen family c
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The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
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