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Product details

Claudin 18.2 Rabbit Polyclonal Antibody

Catalog number ER1902-86

Price for ER1902-86

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Size / count 100 µL

About this product

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

Catalog number
ER1902-86
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Claudin 18 antibody Claudin-18 antibody CLD18_HUMAN antibody CLDN18 antibody SFTA5 antibody SFTPJ antibody
Abbreviation
CLDN18
Swiss Prot
P56856 Human, P56856-2 Human, P56857 Mouse,
Cellular Locus
Cell membrane, tight junction.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide corresponding to N terminal of Human CLDN18.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Rat heart tissue lysates, MG-63, human stomach tissue, mouse stomach tissue, rat stomach tissue, F9.
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000 ;IF-Cell:1:50-1:200 ;IHC-P:1:8,000 ;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 28 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Claudin 18.2 Rabbit Polyclonal Antibody?

The catalog number for Claudin 18.2 Rabbit Polyclonal Antibody is ER1902-86.

What sizes are available for Claudin 18.2 Rabbit Polyclonal Antibody?

Claudin 18.2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Claudin 18.2 Rabbit Polyclonal Antibody in stock?

Claudin 18.2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Claudin 18.2 Rabbit Polyclonal Antibody used for?

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cel

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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