PICK1 Rabbit Polyclonal Antibody

About this product

Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.

Specifications

Catalog number

ER1902-97

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

dJ1039K5 antibody MGC15204 antibody OTTHUMP00000028509 antibody PICK 1 antibody Pick1 antibody PICK1_HUMAN antibody PRKCA binding protein antibody PRKCA-binding protein antibody PRKCABP antibody Protein interacting with C kinase 1 antibody Protein interacting with PRKCA antibody Protein interacting with PRKCA 1 antibody Protein kinase C alpha binding protein antibody Protein kinase C-alpha-binding protein antibody Protein that interacts with C kinase 1 antibody

Abbreviation

PICK1

Swiss Prot

Q9NRD5 Human, Q62083 Mouse, Q9EP80 Rat

Cellular Locus

Cytoskeleton, perinuclear region, membrane, postsynaptic density, synaptosome.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within rat PICK1 aa 280-330.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

SH-SY5Y cell lysate, 293 cell lysate, F9, MCF-7, rat brain tissue, human colon tissue, mouse brain tissue, SH-SY5Y.

Concentration

1 mg/mL

Dilution

WB:1:500-1:1,000;IF-Cell:1:50-1:100;IHC-P:1:50-1:200;FC:1:100-1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size 47/40 kDa.

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No